Scientist II, ADC Medicinal Chemistry

基本情報

求人名

Scientist II, ADC Medicinal Chemistry

勤務地

Tsukuba,Ibaraki

事業部

Oncology Research

雇用形態

正社員

仕事内容

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. （HP:Learn more about Astellas）

Are you driven to make a real difference in the lives of patients?

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

募集の背景 / Purpose & Scope

Recent advances in drug discovery targeting cancer have been remarkable, and Astellas is constantly challenging next-generation modalities such as cell therapy, gene therapy, and multifunctional antibodies, as well as new cancer biology. Under such circumstances, we have successfully delivered innovative treatment drugs such as XOSPATA, XTANDI, and PADCEV to cancer patients.

Furthermore, we are currently promoting drug discovery research by combining multifunctional modality and the biological understanding of TME in the Primary Focus "Immuno-Oncology" established though our Focus Area approach.

We are urgently recruiting people who will participate in the challenge of driving a paradigm shift in cancer treatment together with our team. We welcome applications from those who can persistently plan and carry out research with innovative ideas and a spirit of challenge, and lead research projects as a member of the global team.

職務の内容 / Essential Job Responsibilities

（雇入れ直後）

The position is expected to lead drug discovery programs that utilizes genetically modified technology for cancer treatment, and will be in charge of the following tasks.

1. In view of science and trends in the ADC related field, establish next-generation ADCs that can be expected to have innovative therapeutic benefits
2. Design and synthesis of payloads, linkers and ADCs which includes investigation and analysis of patents, literatures and reviews related to our researching therapeutic area as well as carrying out organic reactions, conjugations, purifications and structure analysis to identify a compound suitable for clinical testing
3. Provides appropriate guidance to younger members on complex issues that arise in ADC research. He/she will also mentor and train younger members of the team in the projects for which he/she is responsible, thereby enhancing the scientific expertise of the team.
4. May be responsible for research outsourced to CROs, such as outsourced synthesis, or in research collaboration with external partners.
5. Contribute to the creation of innovative Oncology Research pipeline through the above ADC research activities.

（変更の範囲）

会社内での全ての業務

【就業環境に関する要件 / Specific Physical or Environmental Requirements】

• This position is based in Tsukuba Research center and will require on-site work.
• (OR) At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines.

応募要件 / Qualifications

必須 / Required

• PhD with 5+ years or MS with 8+ years of relevant experience in medicinal chemistry.
• Strong knowledge of medicinal chemistry
• Experience in serving as a lead chemist in oncology projects
• Experimental skills necessary to carry out ADC research (both small molecule synthesis and ADC conjugation)
• Strong interpersonal and verbal/written communication skills
• Build strong relationships with peers and partners outside
• Business level communication skill in English (Japanese communication skill is not mandatory in case applicants are non-Japanese)

応募書類 / Application Documents

和文履歴書（必須）・和文職務経歴書（必須）・英文レジュメ（任意）

Resumes

選考プロセス / Selection details

書類選考 → 1次面接 → 最終面接

CV screening → First interview → Final interview

• Please be advised that there might be a change in the process.

勤務地 / Location

（雇入れ直後）

茨城県つくば市 アステラス製薬 つくば研究センター

Tsukuba, Ibaraki

（変更の範囲）

会社の定める事業場および自宅

勤務開始日 / Start Date

応相談

Will be decided according to the candidate's flexibility

契約期間 / Contract Duration

期間の定めなし

Not limited to specified period

試用期間 / Probation Period

試用期間原則なし

No probation period in principle

給与 / Salary

①基本給：当人の経歴・技術・技能等を考慮して決定

②裁量労働制の場合：裁量労働手当として職務グレードに応じて50,000～100,000円支給

③フレックスタイム制の場合：月間の所定労働時間を超えて勤務する時間に対して時間外勤務手当を支給

①Base salary: will be decided by the candidate's experience, skill and capability.

②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000～100,000yen, based on the Grade)

③When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.

昇給 / Salary Raise

有り

賞与 / Bonus

有り

諸手当 / Allowance

裁量労働手当、住宅手当、通勤手当 等

Discretionary work allowance, Housing allowance, Commutation allowance, etc.

勤務時間 / Working Hours

8:30～17:30（月～木）、8:30～15:45（金）、専門業務型 裁量労働制

裁量労働制の場合、所定労働時間を働いたものとみなす。

8:30～17:30（Mon～Thu）、8:30～15:45（Fri）

Discretionary Work System

休日 / Holidays

完全週休２日制（土曜・日曜）、祝日、5月1日、夏季、年末年始

Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays

休暇 / Vacation Leave

年次有給休暇、育児休業制度、介護休業制度 等

Annual paid leave, childcare leave system, nursing care leave system, etc.

福利厚生 / Welfare

雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度 等

Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System

アステラス製薬 採用サイト/ Career web site

re-jp.astellas.com/jp/recruit/newgraduates

For more information about Astellas, please visit our career web site.

"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."

What awaits you at Astellas?

• Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
• Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
• Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
• A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organizational Values and Behaviors

Values: Innovation, Integrity and Impact sit at the heart of what we do.

Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.

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